Asparkam - zikuchokera, katundu, zikuonetsa ntchito ndi malangizo

Imodzi mwa mankhwala othandiza kwambiri pa-counter-arrhythmia-kukonza mankhwala ndi Asparkam. Akamanena za zochita zake ndi normalization kagayidwe ndi electrolyte. Ndi metabolite, gwero la potaziyamu ndi magnesium. Chifukwa cha izi, zimayimira kugunda kwamtima. Mankhwalawa ndi a zida za gawo la demokalase kwambiri, koma izi sizimulepheretsa kukhala yothandiza kuposa ma analogu ambiri okwera mtengo. Aspark amakondedwa ndi othamanga kuti athe mwayi wochepetsa mapaundi owonjezera pambuyo pa kuchuluka kwa ulamuliro wakumwa.

Kapangidwe

Asparkam imapezeka ngati mapiritsi ndi yankho la jakisoni. Phukusili muli zidutswa za mapiritsi 50 kapena ma ampoules 10 a 5, 10 ml.

• Piritsi lililonse lili ndi 0,2 g wa potaziyamu ndi magnesium, komanso zowonjezera ku cachet.
• Yankho la Asparkam lili ndi anhydrous magnesium aspartate - 40 mg ndi potaziyamu - 45 mg. Izi ndizofanana ndi 3 mg ya magnesium yoyera ndi 10 mg ya potaziyamu wangwiro. Kuphatikiza apo, mawonekedwe ojambulidwa amakhala ndi sorbitol ndi madzi.

Potaziyamu imapereka mitsempha ya mitsempha, imatulutsa diuretic ndipo imathandiza kwambiri minofu. Magnesium imayang'anira ntchito ya enzymatic, amatenga nawo mbali poyendetsa ayoni ndikukula kwamaselo.

Njira yogwiritsira ntchito ndiyo kukonza njira zamagetsi ndi potaziyamu ndi magnesium. Zinthu izi zimatha kuthana ndi nembanemba yama cell ndikupanga kuchepa kwa ma michere omwe adataya chifukwa chakusintha kwakanthawi kapena kwamatenda. Kukhazikika kwa ma elektrolyte kumabweretsa kuchepa kwa myocardiamu, kuzimitsa chisangalalo chake ndikulola zikhumbo zamagetsi zamachitidwe opangira mtima kuti zizigwira ntchito mwachizolowezi.

Pa nthawi yomweyo, kagayidwe kachakudya njira bwino, ndi atengeke myocardium ndi mtima glycosides amakhala bwino, chifukwa kawopsedwe akutsikira kwambiri. Zombo za Coronary zimathandizanso pakusintha komwe kumachitika, popeza kugunda kwamtima kwamphamvu kumawalola kupereka magazi mulingo woyenera ku ziwalo ndi minyewa yokhala ndi michere ndi mpweya.

Magnesium ions imatsegula ATP, yomwe imayeza kutuluka kwa sodium m'malo osakanikirana ndi potaziyamu m'malo amkati mwake. Kutsika kwa kuchuluka + kwa Na + mkati mwa selo kumatseketsa kusinthana kwa calcium ndi sodium mu minofu yosalala, yomwe imawatsitsimutsa. Kukula kwa K + kumapangitsa kupanga ATP - gwero la mphamvu, glycogen, mapuloteni ndi acetylcholine, yomwe imalepheretsa ischemia wamtima ndi hypoxia wama cell.

Asparkam imalowa m'magazi kudzera m'mimba, ndipo kuchokera pamenepo - ngati aspartate kulowa mu myocardium, pomwe imayamba kugwira ntchito kukonza kagayidwe kake.

Katundu

Zimachitika chifukwa chophatikizira kwa potaziyamu ndi magnesium paminyewa yamtima ndikuthandizira kuyibwezeretsa pambuyo podwala mtima. K + imakulitsa mgwirizano wamtima pochepetsa kuchepa komanso kukonza magwiridwe antchito am'mimba. Imakulitsa kuwala kwa zotengera zazikulu za mtima. Magnesium imathandizira kuphatikizika kwa ma amino acid ofunikira pakubwezeretsanso vuto la minofu ndikulimbikitsa magawano am'magazi, zomwe zimapangitsa kuti kusinthika msanga.

Katunduyu amagwiritsidwa ntchito pochiza khungu komanso kuthamanga kwambiri. Kukhazikika kwa kagayidwe kake ndi kusungunuka kwa ma electrolyte kumathetsa pafupifupi zizindikilo zoyipa zomwe zimakhudzana ndi kuchuluka kwa mitsempha. Zotsatira zoyipa ndikukula msanga kwa minofu, komwe kwatsimikizika kuti ndikofunikira kwa othamanga. Chifukwa chake, Asparkam ndiyotchuka pamasewera amagetsi.

Potaziyamu ndi magnesium

Akatswiri azachipatala nthawi zonse amalankhula zakufunika kwa zinthu izi. Palibe chodabwitsa mu izi. Phokoso la mapangidwe amtima limatsimikizika ndi ntchito yabwino kwambiri yamakina opitilira m'mnyewa wamtima, momwe zimakhalira zokha, ndipo, podutsa mitolo ya mitsempha yapadera, imathandizira kuchuluka kwa kupindika kwa atria ndi ma ventricles munthawi inayake. Kuchita bwino kwa ulusiwu kumatengera kuchuluka kwa magnesium ndi potaziyamu mkati mwake.

Kugunda kwa mtima kumakhala bwino, zomwe zikutanthauza kuti munthuyo amamvanso bwino, chifukwa chiwalo chilichonse chimalandira chakudya choyenera komanso mpweya wabwino munthawi yake komanso motsatizana bwino. Ndikusowa kwa magnesium, mavuto amayamba m'mitsuko yamatenda. Amafewa ndikukula. Zotsatira zake, magazi amachedwetsa kuyenda kwake, ziwalo zimayamba kusapeza bwino, ndipo wodwalayo amayamba kumva kuwawa.

Zotsatira zake zimawonedwa ndi potaziyamu owonjezera: ma coronaries amakhala osalimba komanso opapatiza. Koma izi zimabweretsanso mavuto pamavuto amwazi, chifukwa magazi sangathe kulowa m'misewu yayikulu mokwanira ndikupopedwa kumaziwalo. Kutaya kwa magnesium ndi maselo, kutulutsidwa kwake m'malo ophatikizika kumaphatikizapo kuwonongeka kwa chakudya chambiri, hyperkalemia imachitika.

Magnesium imagwira nawo mbali zonse zamagetsi popanda kusiyanasiyana. Ndi chothandizira pakugawika kwama cell, RNA kaphatikizidwe, ndipo chimapereka chikhomo chazidziwitso zakubadwa. Koma ngati ndende yake icheperachepera, nembanemba ya selo limakhala chopinga chosagonjetseka pazomwe zimafufuza. Aspark magnesium imathandizira kulowa mmenemo ndi kuchuluka kwa zinthuzo.

Pali mbuna pano. Kuchuluka kwa mankhwalawa kumadzaza ndi hypermagnesemia, ndipo ichi ndi chifukwa chomangidwa ndi mtima. Chifukwa chake, kudzipatsa nokha mankhwala "osavulaza" sikulandirika.

Kuchuluka kwa potaziyamu ndi magnesium m'chipindacho ndikofunikira makamaka panthawi yapakati. Amaonetsetsa kuti mwana wosabadwayo akukula bwino. Koma Asparkam amapatsidwa kwa amayi apakati mosamala kwambiri, posankha Chijeremani Panangin - vitamini wamtima. Zizindikiro zambiri monga kutopa ndi dysuria.

Vuto lina: kusowa kwa potaziyamu kumasintha chisangalalo chamanjenje, komanso kuchepa kwa magnesium yama cell kumayambitsa kusamvana pakudya ndikugwiritsa ntchito mphamvu, komwe kumapangitsa kugwedezeka, kufooka kwa miyendo, ndi ulesi.

Zikuonetsa kuti asparkam

Ntchito yayikulu ya Asparkam ndikutumiza zinthu zomwe zimafufuza. Mankhwalawa amalembedwa pazochitika zotsatirazi:

• Kuperewera kwa K + ndi Mg + m'thupi.
• Matenda a mtima.
• Ischemic matenda amtima, postinfarction chikhalidwe.
• Zowonjezera zamitsempha yamagetsi.
• Tsankho la Foxglove.
• Dziko lowopsa.
• Matenda azizungu aakulu.
• Matenda a Atrial.
• Mtima kulephera.
• Kuyambira miyezi inayi ndikulimbikitsidwa kuphatikiza ndi Diacarb kuti athetse kukakamizidwa. Kuphatikizana kumeneku kumagwiritsidwa ntchito pochizira khungu, khunyu, edema, gout.

Masewera

Izi sizikutanthauza kuti Asparkam imakhudza kwambiri phindu la minofu. Chifukwa chake, mwamalingaliro, pamasewera si mankhwala osankha. Komabe, kutchuka kwake pakati pa othamanga ndikwabwino. Malongosoledwe ake ndiosavuta: akapeza mapaundi owonjezera, othamanga amadya ma calorie ambiri ngati mapuloteni, chakudya, ndi mafuta. Pa nthawi imodzimodziyo, kufufuza zinthu kumapangitsa gawo laling'ono kwambiri la zakudya. Ndizokwanira kuchita zochitika zamtima. Kuphatikiza apo, kuchepa kwa potaziyamu ndi magnesium kumabweretsa kutopa kwambiri chifukwa cha kusayanjana kwamagetsi. Aspark pankhaniyi sangasinthe.

Yaying'ono, yosavuta kugwiritsa ntchito komanso yodzaza ndi kukonzekera kwa K + ndi Mg +:

1. Imachepetsa kutopa.
2. Amalipira zoperewera zama micronutrient.
3. Imachepetsa kufooka kwa minofu.
4. Zimapangitsa kuti myocardium igwire ntchito mokhazikika.
5. Zimalimbikitsa kupirira.
6. Imalepheretsa AMI ndi ONMK.

Kumanga thupi

Pankhani yolimbitsa thupi, apa Asparkam amakhala ngati metabolite wabwino kwambiri. Ndikulimbitsa mphamvu komwe mbali yake yomanga minofu ikufunika. Potaziyamu imathandizira kwambiri kuthamanga kwa kagayidwe kachakudya, magnesium imakhudzidwa ndi kagayidwe kake ka protein. Poterepa, kukula kwama cell kumachitika popanda kudzikundikira kwamafuta ndikusunga kwamadzi m'thupi. Imeneyi ndi mfundo yofunika kwambiri, chifukwa pa nthawi ya masewera othamanga kudya wambiri madzi, amene amatsuka kufufuza zinthu. Izi zikutanthauza kuti kukonzanso kwawo kumakhala kofunikira mwachangu.

Kuchepetsa thupi

Kulingalira kogwiritsa ntchito mankhwalawa kumachokera kuzinthu zomwe zimadziwika kale za magnesium ndi potaziyamu. Mg + imafunika ndi dongosolo lalikulu la manjenje, ndipo K + imathandiza minofu yonse mthupi. Pamodzi amakonza madzi amchere amchere, amachotsa kutupa. Chifukwa cha izi, Asparkam imagwiritsidwa ntchito pochepetsa thupi: kuchotsa madzimadzi mthupi kumakuthandizani kuti muchepetse thupi. Nthawi yomweyo, kuchuluka kwamafuta amthupi sikusintha, chifukwa chake mankhwalawa sanakhalepo ndi njira zomwe zimathandizira kuonda. Kuzitenga mosaganizira ndizowopsa, chifukwa ndi metabolite, ndipo kagayidwe kake kagwiritsidwe ndi chinthu chobisika kwambiri. Kuchulukitsa zinthu kumafunikira zotsatira zosafunikira, koma sizimathandizira njira zamagetsi.

Contraindications ndi njira ya makonzedwe

Pali zotsutsana zochepa, koma ndizofunikira:

• Kusalolera kwamunthu kapena kulimbitsa thupi.
• Kulephera kwa adrenal glands ndi impso.
• Myosthenia.
• Kusokonezeka kwamtima.
• Kutsekereza madigiri 2-3.
• Matenda a acidosis.
• ARF ndi kulephera kwa impso, anuria.
• Kutulutsa magazi.
• Kutaya madzi m'thupi.
• Zaka zosakwana 18.

Mphamvu ya Asparkam pa thupi silinaphunzire mwatsatanetsatane. Pachifukwa ichi, amagwiritsidwa ntchito mosamala panthawi yapakati ndipo sanapatsidwe kwa ana. Odwala okalamba nawonso ali pachiwopsezo, chifukwa kagayidwe kake ka thupi kachedwetsedwa a priori chifukwa cha kusintha kwazaka. Komabe, m'matenda amtima, wothandizirayo amavomerezedwa kuti alandire popanda zoletsa. Njira yachizolowezi ndikumwa mapiritsi angapo katatu patsiku mutatha kudya.

Zotsatira zoyipa

Asparkam imangokhala ndi zovuta zokha, komanso zoyipa. Amawonekera ndi zizindikiro zotsatirazi:

Kumva kufooka, kufooka, chizungulire.

• Minofu kufooka.
• Ziphuphu pakhungu.
• Nseru.
• Dyspepsia.
• Pakamwa pouma.
• Kuphulika.
• Kutengeka.
• Matenda a Hyperhidrosis.
• Dyspnea.
• Mitsempha ya thrombosis.

Komanso, ambiri osokoneza n`zotheka, amene kumaonekera:

• matenda;
• hypermagnesemia;
• kapezi masaya;
• ludzu;
• arrhythmia;
• kugwedezeka;
• kuthamanga kwa mitsempha;
• mtima;
• maganizo a likulu la kupuma mu ubongo.

Zizindikirozi zimafunikira upangiri kuchipatala. Mwambiri, kugwiritsa ntchito Asparkam kwa nthawi yayitali kumafunikira kuwunika milingo ya electrolyte, popeza:

1. chitetezo chokwanira cha mankhwala sichinatsimikizidwe;
2. Akaphatikizidwa ndi tetracyclines, iron ndi fluorine, mankhwalawa amaletsa kuyamwa kwawo (nthawi yapakati pa mankhwala iyenera kukhala osachepera maola atatu);
3. pali chiopsezo chokhala ndi hyperkalemia.

Ngakhale

Ili ndi cholinga chosiyana. Malinga ndi malingaliro a pharmacodynamics, kuphatikiza ndi okodzetsa, beta-blockers, cyclosporins, NSAIDs, heparin kumapangitsa kukula kwa asystole ndi arrhythmia. Kuphatikiza kwa mahomoni kumayimitsa izi. Potoniyamu ayoni amachepetsa zotsatira zoyipa zama glycosides amtima. Magnesium ayoni - neomycin, streptomycin, polymyxin. Calcium imachepetsa ntchito ya magnesium, chifukwa chake muyenera kuphatikiza ndalamazi mosamala kwambiri, pazifukwa zathanzi.

Pharmacokinetics imachenjeza za kusagwirizana kwa Asparkam ndi mankhwala osokoneza bongo komanso otsekemera, chifukwa amachepetsa kuyamwa kwa mankhwala mu chubu la m'mimba ndipo amalimbikitsa, ngati kuli koyenera, kuti azikhala ndi maola atatu pakati pa mankhwala.

Poyerekeza ndi Panangin

Potaziyamu ndi magnesium amapezekanso mu mankhwala ena otchuka. Tikukamba za Panangin. Makhalidwe ofanana ndi mankhwalawa amaperekedwa patebulo.

Zikuwonekeratu kuti zinthu zomwe zimagwira ntchito m'mankhwala onsewa ndizofanana, kusiyana kuli m'khola, zomwe sizimakhudza mankhwala. Komabe, Panangin ali ndi nembanemba yamafilimu yomwe imateteza mucosa wam'mimba ndi mano ku poizoni wa mankhwala. Chifukwa chake, aliyense amene ali ndi vuto ndi njira yogaya chakudya amalimbikitsidwa Panangin, womwe mtengo wake umakhala wokwera kangapo kuposa mtengo wa Asparkam.