Kodi serotonin ndi chiyani ndipo chifukwa chiyani thupi limafunikira

Serotonin amatenga nawo gawo pazochita zamunthu komanso momwe amakhalira. Sizachabe kuti dzina linapatsidwa dzina lina - "hormone ya chisangalalo". Komabe, chophatikizachi chimakhala ndi mawonekedwe ambiri pazakuthupi. Ngakhale kupindika koyamba kwa minofu yamtima mwa mwana wosabadwa m'mimba kumayambitsa serotonin. M'nkhaniyi, tikambirana za ntchito zazikulu za mahomoni, komanso zinthu zomwe zimakhudza gawo lake komanso chizolowezi chake.

Serotonin ndi chiyani

Serotonin (5-hydroxytryptamine, kapena 5-HT) ndi biogenic amine. Zonsezi ndizomwe zimayambitsa matenda a ubongo komanso otchedwa "effector" hormone. Izi zikutanthauza kuti chinthucho ndichofunikira kuti thupi lizisamutsa chidziwitso pakati pa ma neuron aubongo, komanso kuwongolera momwe ziwalo ndi machitidwe amagwirira ntchito: mtima, kugaya chakudya, kupuma ndi ena. Oposa 90% ya mahomoni amapangidwa ndi m'matumbo mucosa, enawo ndi pineal gland (pineal, kapena pineal, gland).

Mthupi la munthu, mamolekyulu a serotonin amalimbikira m'mitsempha yapakatikati, minofu, ma adrenal gland, ndi ma platelets.

Mankhwala amtundu wa serotonin: C₁₀H₁₂N₂O

Molekyu ya mahomoni imakhala yosavuta. Mothandizidwa ndi michere, mankhwalawa amapangidwa kuchokera ku tryptophan, amino acid wofunikira womwe thupi lathu silimapanga lokha. Munthu amatenga tryptophan yokwanira m'njira imodzi yokha - mwa kudya zakudya zomwe zili ndi amino acid.

Tryptophan, nayonso, imaphatikizana ndi ma amino acid ena, imagwirizana ndi chitsulo ndipo imalowa munthawi yamanjenje. Kuti muwoloke chotchinga magazi ndi kulowa muubongo, pamafunika insulini.

Wothandizira wamkulu pakuphatikiza kwa serotonin kuchokera ku amino acid ndi dzuwa ndi vitamini D. Izi zikufotokozera kupezeka kwanyengo zanyengo, pomwe nthawi yophukira komanso nthawi yozizira pamakhala kuchepa kwa vitamini.

Ntchito ndi kagwiritsidwe kake ka mahomoni

Pali mitundu ingapo yayikulu yama serotonin receptors ndi ma subspecies ambiri. Kuphatikiza apo, ndiosiyanasiyana kotero kuti ena amakhala ndi zotsutsana kwathunthu.

Ena mwa mapulogalamuwa amatchulidwa kuti ndi otsegulira, pomwe enawo amakhala ndi mphamvu zoletsa.

Mwachitsanzo, serotonin imakhudzidwa ndikusintha kuchoka ku tulo kupita pakudzuka komanso mosemphanitsa. Zili ndi zotsatira zofananira pamitsempha yamagazi: imakulitsa pakamveka kamvekedwe kakang'ono kwambiri ndipo imachepetsa ikatsika.

Serotonin imakhudza pafupifupi thupi lonse. Ntchito zofunika kwambiri za mahomoni:

• imayambitsa kupweteka - anthu omwe ali ndi serotonin receptors amalolera kupweteka bwino;
• kumapangitsa kulimbitsa thupi;
• kumawonjezera kutseka magazi, kuphatikiza mawonekedwe a magazi pamalo a mabala otseguka;
• amayang'anira chapamimba motility ndi matumbo peristalsis;
• mu dongosolo la kupuma, amayang'anira njira yopumulira ya bronchi;
• amayendetsa kamvekedwe ka mtima;
• amatenga nawo mbali pobereka (wophatikizidwa ndi oxytocin);
• amachititsa kukumbukira kwanthawi yayitali ndikuzindikira;
• imathandizira libido yachibadwa mwa abambo ndi amai, komanso ntchito zobereka;
• zimakhudza thanzi lamalingaliro ndi malingaliro amunthu;
• Amapereka mpumulo wabwino pogona;
• imapereka chidziwitso chokwanira cha dziko lozungulira komanso malingaliro abwino;
• amalamulira chilakolako (gwero - Wikipedia).

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Zotsatira za mahomoni pamalingaliro ndi malingaliro

Chisangalalo, mantha, mkwiyo, chisangalalo kapena kukwiya ndi malingaliro amisala komanso njira zokhudzana ndi thupi. Maganizo amalamulidwa ndi mahomoni. Mwanjira imeneyi, pakusintha, thupi la munthu laphunzira kuthana ndi zovuta zachilengedwe, kusintha, kukhazikitsa njira zodzitetezera komanso kudziteteza.

Serotonin imakhudza kusinthasintha. Ndizodziwika bwino, zomwe zimawerengedwa pazinthu masauzande ambiri: malingaliro abwino ndi malingaliro abwino amaphatikizidwa ndi milingo yayikulu ya mahomoni achimwemwe. Komabe, zinthu sizophweka. Mosiyana ndi "mnzake" dopamine, serotonin siyambitsa magwiridwe antchito abwino.

Mahomoni amachititsa kuti anthu asamangokhalira kukhumudwa komanso kupondereza ntchito zawo m'magulu osiyanasiyana a ubongo, kuteteza kuvutika maganizo.

Nthawi yomweyo, imapangitsa kuti minofu ikhale yolimba, chifukwa chake munthu amatha kumva kuti "Nditha kusuntha mapiri."

Malinga ndi zotsatira za kafukufuku wina, asayansi adanenanso kuti malowa m'malo otsogola, kapena utsogoleri ndi ulamuliro, zimadaliranso pamlingo wa izi. (gwero mu Chingerezi - Sage Journal).

Mwambiri, mphamvu ya serotonin pamikhalidwe yathu yamaganizidwe ndi yayikulu kwambiri. Kuphatikiza ndi mahomoni ena, zimathandiza kukhala ndi malingaliro osiyanasiyana: kuyambira pachisangalalo mpaka kumaliza chisangalalo, kapena, kutero, kukwiya, ziwawa, komanso kupalamula milandu. Pazovuta, munthu yemwe ali ndi vuto lochepa la serotonin amakumana kwambiri ndikumva kuwawa kwambiri. Ndiye kuti, timadzi timeneti timathandizanso pakudziletsa komanso kutengeka mtima.

Mlingo wa serotonin m'thupi

Muyeso waukulu wa serotonin, monga mahomoni ena ambiri, ndi ng / ml. Chizindikiro ichi chikufotokozera kuchuluka kwa ma nanograms azinthu zomwe zili mu mililita 1 ya plasma. Kuchuluka kwa mahomoni kumasiyanasiyana - kuyambira 50 mpaka 220 ng / ml.

Kuphatikiza apo, muma laboratories osiyanasiyana, ziwerengerozi zimatha kusiyanasiyana kutengera ma reagents ndi zida zomwe agwiritsa ntchito. Chifukwa chake, kuzindikira zotsatira ndi ntchito ya katswiri.

cholozera... Kafukufuku wamagazi am'magazi amafunikanso ngati wodwalayo sakuganiza kuti ali ndi nkhawa, koma zotupa zoyipa m'mimba ndi m'matumbo. Kufufuza kumaperekedwa kokha pambuyo pa maola 12 a njala. Dzulo lake, ndizoletsedwa kumwa mowa, kusuta, komanso milungu iwiri isanachitike kumwa mankhwala aliwonse.

Momwe zinthu zakunja zimakhudzira milingo ya serotonin

Chifukwa chake, "zopangira" zazikulu zopangira serotonin ndi amino acid tryptophan. Chifukwa chake, zakudya za anthu zimathandizira kwambiri pakupanga mahomoni. Chofunika tsiku lililonse la tryptophan ndi 3-3.5 mg pa 1 kg ya kulemera kwa munthu. Chifukwa chake, mayi wokhala ndi makilogalamu 60 ayenera kudya 200 mg ya amino acid ndi chakudya. Mwamuna wolemera makilogalamu 75 - 260 mg.

Ma amino acid ambiri amapezeka m'mapuloteni ochokera kuzinyama.

Ndiye kuti, nyama, nsomba, nkhuku ndi tchizi. Pakati pa atsogoleri kuchuluka kwa tryptophan, tidasankha:

• ofiira, wakuda caviar;
• chokoleti;
• nthochi;
• mtedza;
• mankhwala mkaka;
• apricots zouma.

Tsitsani tebulo mwatsatanetsatane lazogulitsa ndi chizindikiritso cha tryptophan zomwe mumagwiritsa ntchito tsiku lililonse pano.

Kuti afulumizitse kaphatikizidwe ka serotonin mwa anthu, makamaka omwe amakhala ndi nkhawa, madokotala amalimbikitsa kuti azichita zolimbitsa thupi ndikupeza nthawi yambiri padzuwa.

Kuthamanga mothamanga, kulimbitsa thupi, kuchita masewera olimbitsa thupi m'mawa, komanso, maphunziro ophunzitsira samangolimbikitsa, komanso amalimbikitsanso thupi la serotonin.

Munthu akamachita masewera olimbitsa thupi, serotonin imapangidwa kwambiri. Izi zimapangitsa minofu kukhala yolimba ndikuwonetsetsa kuti thanzi likukhala labwino, kuphatikiza pamaganizidwe.

Ndikofunika kudziwa! Kuchita masewera olimbitsa thupi mopitirira muyeso kumakhala ndi zotsatirapo zake: kumachedwetsa kupanga serotonin. Chifukwa chake, nthawi yabwino yophunzitsira pamlingo woyenda ndi mphindi 45-60.

Zomwe zimachitika ndikuchepa kwa mahomoni

Kuda nkhawa, kukwiya, kunyalanyaza, komanso kuzengereza kosatha ndi zizindikilo zowonekera kwambiri za kuchepa kwa serotonin. Kulumikizana pakati pa kuchepa kwa mahomoni ndi kukhumudwa ndi malingaliro ofuna kudzipha kwatsimikiziridwa m'maphunziro asayansi (gwero mu Chingerezi - PubMed).

Komabe, pali zizindikiro zambiri zomwe sizimakhudzana nthawi zonse ndi kusowa kwa serotonin, koma mwina chifukwa cha chifukwa chomwechi:

1. Migraine. Kudya tryptophan kosakwanira nthawi zambiri kumakhala muzu wa matendawa.
2. Kusakwiya pang'ono. Kuperewera kwa serotonin kumabweretsa kuchepa kwa calcium. Zikatero, minofu yam'mimba imafooka, zomwe zimapangitsa kuchepa kwa funde la peristaltic. Komanso, kusowa kwa serotonin kumafuna kuwonongeka kwa katulutsidwe m'matumbo.
3. Matenda okhumudwitsa ndi amodzi mwamavuto ambiri masiku ano m'zaka zaposachedwa. Nthawi zambiri amatsagana ndi zopweteka za m'mimba komanso zovuta zam'mimba.
4. Zovuta za chitetezo cha mthupi. Amawonetsedwa ndi ARVI wokhazikika, matenda otopa, kusafuna kuchita chilichonse, komanso kuchepa kwa minofu.
5. Kulimbitsa ziwonetsero zosasangalatsa za PMS mwa akazi.
6. Kusowa tulo. (nayi tsatanetsatane wazomwe mungachite ngati mukudwala matenda osowa tulo mukatha kuchita masewera olimbitsa thupi).
7. Kuzindikira ndi kukumbukira kukumbukira.
8. Mavuto akhungu, makamaka ana.
9. Kuchulukitsa kwa toxicosis mwa amayi apakati.
10. Kukula kwa kulakalaka mowa, mankhwala osokoneza bongo.

Ndikuchepa pang'ono kwa serotonin, madokotala amalimbikitsa kuti ndiyambe ndi kusintha kwa zakudya ndi kuchita masewera olimbitsa thupi pafupipafupi. Nthawi zina zowonjezerazo zimathetsa vutoli. Pazovuta zazikulu, mankhwala opatsirana pogonana amalembedwa. Ngakhale zochita zawo nthawi zambiri sizongowonjezera kukula kwa mahomoni achimwemwe, koma pakugawana bwino pakati pa maselo. Chithandizo cha mankhwala otchedwa serotonin reuptake inhibitors (sertraline, paroxetine, fluoxetine) ndi apakhungu.

Zindikirani! Ngati munthu ali ndi vuto la kukhumudwa, ndiye kuti ngakhale chakudya chochuluka kwambiri cha tryptophan sichimuthandiza.

Matenda okhumudwa ndi zovuta zomwe zimayambitsa matenda amadzimadzi. Zotsatira zake, tryptophan siyabwino m'thupi la munthu ndipo siyimasinthidwa kukhala serotonin. Chifukwa chake, chithandizocho chimaperekedwa ndi dokotala woyenera, pomwe zakudya zimangokhala njira yothandizira kuchira.

Mawonetseredwe a milingo yokwera ya serotonin

Kuchulukitsa kwa serotonin ndizovuta zomwe zimachitika kawirikawiri. Vutoli limayambitsidwa ndi izi:

• mankhwala osokoneza bongo a antidepressants kapena mankhwala okhala ndi mankhwala osokoneza bongo;
• matenda oncological;
• kutsekeka m'matumbo.

Pachiyambi, kudumpha kwakukulu kwa mahomoni, kapena matenda a serotonin, kumapangitsa kusintha kwa mankhwala ena kupita ku china kapena mlingo wolakwika. Komabe, nthawi zambiri zimachitika chifukwa chodzilimbitsa komanso kusankha mankhwala molakwika.

Matendawa amadziwika m'maola oyamba, koma nthawi zina (makamaka okalamba) zizindikiro zoyambirira zimawoneka masana. Vutoli ndi loopsa komanso lakupha.

Kutengeka kwakukulu kumawonekera, kuseka nthawi zambiri kumalowetsa misozi. Munthuyo amadandaula za mantha komanso nkhawa zomwe sizikugwirizana ndi zomwe zimayambitsa. Pazovuta zazikulu, kuyenda kwamayendedwe kumakhala kovuta, kusokonekera, kuyerekezera zinthu koyambira kumayamba, ndipo, monga chiwonetsero chowopsa, kugwa khunyu.

Ndi njira yoyipa yowopsa, kuwonjezeka kwakukulu kwa kuthamanga kwa magazi kumatenda apamwamba, tachycardia, zovuta zazikulu zamagetsi, zomwe zimapangitsa kuti mukhale ndi matenda am'magazi, magazi, komanso mantha.

Zikatere, pamafunika chithandizo chofulumira. Odwala amaletsa mankhwala omwe amachititsa kuti serotonin ipangidwe, yongowonjezera vutoli (kuthamanga, kutentha, kugunda kwa mtima). Nthawi zina m'mimba mumatsukidwa kuti muchepetse kuledzera.

Mapeto

Maselo a Serotonin komanso kusangalala, oddly mokwanira, amakhala ndi zotsatira zoyanjana. Chifukwa chake, kukhala ndi malingaliro abwino m'moyo, nthabwala, kutha kusangalala ndi zinthu zazing'ono kumathandizira kukhalabe ndi mahomoni ofunikira. Kuseka, idya moyenera, kuyenda kwambiri nyengo yotentha, kuchita masewera olimbitsa thupi mumlengalenga. Kenako ma serotonin receptors anu azigwira ntchito bwino, kukuthandizani kukhala ndi moyo ndikusunthira kuzolinga zilizonse ndi malingaliro abwino!

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