Glucosamine ndi chinthu chomwe cholinga chake ndikuteteza kutupa kwamafundo ndi mafupa, kukulitsa moyo wokangalika. Kafukufuku wazinyama awonetsa kuti zitha kukulitsa moyo wautali pakati pa mbewa, makoswe, hookworms ndi ntchentche. Kugwiritsidwa ntchito kwake mwa anthu kumachedwetsa ukalamba wa mafupa.
Kodi glucosamine ndi chiyani?
Glucosamine ndichinthu chachilengedwe chomwe chimapezeka m'malo olumikizana ndi mafupa a nyama. Idapezeka koyamba mu 1876 ndi dokotala waku Germany a George Ledderhoes. Amakhala ofunikira kwambiri mthupi monosaccharide ndi amino acid - shuga ndi glutamine.
Maselo a cartilage amagwiritsa ntchito glucosamine ngati pakatikati popanga hyaluronic acid, proteoglycans, ndi glycosaminoglycans. Kuyambira zaka za m'ma 60 zapitazo, asayansi aganiza zogwiritsa ntchito mankhwalawa kuti abwezeretse khungu ndi malo olumikizirana mafupa, komanso kuchiza arthrosis. Kufufuza kwakukulu kunayamba, zotsatira zake zinali zotsutsana.
Kafukufuku wopangidwa mu 2002-2006 ku America adatsimikizira kuti palibe chithandizo chamankhwala cha arthrosis. Katunduyu adatchedwa "wotsutsana" chifukwa cha mankhwala ake opatsa chidwi. Madokotala amalangiza kuti mukane kuwamwa ngati zotsatira zomwe mukuyembekezera sizinabwere patatha miyezi 6 mutayamba kumwa mankhwalawo.
Fomu yotulutsidwa
Zakudya zowonjezerazo zimapezeka m'mapiritsi kapena ufa wokonzekera yankho. Njira yachiwiri ndiyabwino kwambiri, chifukwa imachita mwachangu.
Ufa odzaza m'matumba osindikizidwa a 3.5 g; Zidutswa 20 pa bokosi. Thumba lililonse limakhala ndi 1.5 g wa chinthu chogwira ntchito.
Kutenga chowonjezeracho kumakhudza pokhapokha mukamatsata malingaliro a dokotala wanu. Mlingo womwe ukuwonetsedwa m'malamulo amatsatiridwa mosamalitsa, pokhapokha ngati ataperekedwa ndi dokotala. Kudzipatsa nokha sikuvomerezeka.
Kapangidwe
Mtundu uliwonse wa mankhwala lili waukulu yogwira pophika - glucosamine sulphate. Zothandiza zigawo zikuluzikulu: sorbitol, aspartame, ndi zina zotero. Zimatsimikizira kuyamwa kwabwino kwa thupi.
Pharmacological kanthu ndi pharmacokinetics
Glucosamine imathandizira matumbo a khungu kuti athane ndimavuto amachitidwe komanso kusintha kwakukalamba, kumathandizira kubwezeretsa mafupa ndi khungu.
Pafupifupi 90% ya zinthuzo imadzilowetsa m'matumbo, pomwe gawo lomwe limagwira kwambiri limapezeka mu impso, mitsempha ndi chiwindi. Kuchotsa mankhwala m'thupi kumachitika mothandizidwa ndi impso ndi kwamikodzo. Kugwiritsa ntchito zowonjezera mavitamini sikungakhudze magwiridwe antchito amtima, kupuma ndi manjenje.
Zikuonetsa ntchito
Nthawi zambiri, chisonyezo chachikulu chowonjezerapo ndikumva kuwawa, kutayika kwa mayendedwe abwinobwino.
Zotsutsana
Zotsutsana nthawi zambiri zimalumikizidwa ndi izi:
- chizolowezi chifuwa;
- tsankho munthu zigawo zikuluzikulu;
- matenda a impso;
- phenylketonuria.
Glucosamine ndi yoletsedwa kwa ana ochepera zaka 15.
Mimba ndi mkaka wa m'mawere
Munthawi yoyamba ya mimba, mankhwalawa amaletsedwa kugwiritsa ntchito azimayi. Mu II ndi III, phwando limatheka pokhapokha phindu lomwe lingachitike kwa mtsikanayo litapitirira ziwopsezo za khanda.
Zinthu zogwiritsira ntchito zimalowa mkaka wa m'mawere. Kulandila kwake ndikotheka panthawi yoyamwitsa, koma kuyamwitsa kuyenera kuyimitsidwa mukamalandira chithandizo.
Njira ya makonzedwe ndi mlingo
Njira yothetsera ufa imasungunuka mu kapu yamadzi oyera. Thumba limodzi limadyedwa tsiku lililonse. Malangizo oyendetsera munthu amaperekedwa ndi dokotala, nthawi zambiri mankhwala amatenga miyezi yosachepera 1-3, kutengera kukula kwa matendawa. Njira yachiwiri ndiyotheka miyezi iwiri kuchokera koyambirira. Chithandizo ndi mankhwala nthawi zambiri chimakhala chotalikirapo ndipo kusintha koyamba kumachitika, makamaka, pambuyo pa milungu 1-2 kuyambira pomwe amalandila.
Pogwiritsa ntchito mapiritsi, mankhwalawa amatengedwa ndi zakudya, kumwa madzi ambiri. Mlingowu umatsimikiziridwa ndi dokotala yemwe akupezekapo. Nthawi zambiri, odwala akulu amapatsidwa kapisozi 1 kamodzi patsiku. Kutalika kwa mankhwala kumatha kusiyanasiyana kwa miyezi 3 mpaka 6.
Zotsatira zoyipa ndi bongo
Nthawi zambiri, mankhwalawa amalowetsedwa m'thupi ndipo amalekerera. Komabe, zosasangalatsa mbali zimachitika mu mawonekedwe a kusokonezeka m'mimba, mutu, chizungulire ndi kuchuluka khungu tilinazo. Ngati zimachitika, muyenera kufunsa dokotala.
Kwa nthawi yonse yogwiritsira ntchito zowonjezera mavutowa, palibe vuto limodzi lomwe limadziwika. Pakakhala zosasangalatsa mutalandira mankhwalawa, muyenera kutsuka m'mimba ndikumwa mankhwala osokoneza bongo. Kenako pitani kwa dokotala.
Kuyanjana ndi mankhwala ena ndi zodzitetezera
Pogwiritsidwa ntchito munthawi yomweyo ndi mankhwala a tetracycline mndandanda, glucosamine imalimbikitsa kuyamwa kwawo mwachangu. Zinthu zosiyanazi zimawonedwa ndi penicillin ndi chloramphencol, mawonekedwe awo, m'malo mwake, amachepetsa. Mphamvu yakumwa mankhwala osagwiritsa ntchito anti-steroidal imalimbikitsidwa kwambiri, ndipo zotsatira zoyipa za corticosteroids pamatumba a cartilage zimachepa.
Ndikofunika koyamba kufunsa dokotala wanu za kumwa mankhwala. Kwa anthu onenepa kwambiri, mlingowo umakulitsidwa kuti akwaniritse chithandizo chake. Kuteteza kwa nthawi yayitali kumafunika.
Zinthu zosungira ndi moyo wa alumali
Sungani zinthuzo kutali ndi ana, popewa kuwala kwa dzuwa. Kutentha mchipinda kuyenera kukhala mkati mwa + 15- + 30 degrees.
Mutha kusunga mapiritsi kwa zaka 5, ndi ufa pokonzekera yankho - zaka zitatu.
Malamulo operekera ku pharmacies
Chogulitsacho chimagulitsidwa kokha ndi mankhwala.
Analogs mu Russian Federation, USA ndi Europe
Ndi dokotala yekha yemwe angakuthandizeni kusankha mankhwala omwe ali ndi zofanana kapena zofanana. Odziwika kwambiri masiku ano ndi Artrakam, Dona, Artiflex, Elbona, Union ndi ena.
Makampani opanga mankhwala amakono amapereka mitundu yosiyanasiyana ya kukonzekera kwa glucosamine sulphate. M'mayiko aku Europe, glucosamine ali ndi udindo wa mankhwala osokoneza bongo, ndipo ku United States, ali ndi zowonjezera zowonjezera. N'zochititsa chidwi kuti kuchuluka kwa mankhwala mu zakudya zowonjezera ku America ndipamwamba kuposa mankhwala a ku Ulaya.
Zida zopangidwa ndi Glucosamine zaphunziridwa kwazaka zopitilira khumi. Asayansi ndi madokotala ambiri amaganiza kuti zotsatira za mankhwalawa ndizotsutsana. Titha kunena motsimikiza kuti imagwiradi ntchito, koma mtengo wazowonjezera nawo nthawi zambiri umakhala wokwera kwambiri.