Acetyl-carnitine (Acetyl-L-carnitine kapena ALCAR mwachidule) ndi mtundu wa ester wa amino acid L-carnitine komwe gulu la acetyl limalumikizidwa. Opanga masewera owonjezera omwe ali ndi ALCAR amati mtundu wa L-carnitine ndiwothandiza kwambiri pakugwiritsa ntchito masewera, popeza umakhala ndi kupezeka kwapamwamba kwambiri, chifukwa chake utha kugwiritsidwa ntchito pochepetsa kuchepa komwe kumakhala ndi zotsatira zomwezo. Komabe, ziyenera kukumbukiridwa kuti izi sizinatsimikizidwe.
Makhalidwe a mawonekedwe a acetyl, kusiyana pakati pa L-carnitine ndi acetylcarnitine
Acetylcarnitine ndi L-carnitine ndi mitundu iwiri yosiyana ya mankhwala omwe amakhala ndi mankhwala ofanana koma amasiyana pamitundu.
L-carnitine
L-carnitine (levocarnitine) ndi amino acid, chophatikiza chokhudzana ndi mavitamini a B, ndipo ndichimodzi mwazomwe zimalumikizana kwambiri ndi kagayidwe ka mafuta m'maselo. Izi zimalowa m'thupi la munthu ndi chakudya (nyama, mkaka ndi zopangira mkaka, nkhuku), komanso zimapangidwanso m'chiwindi ndi impso, pomwe zimaperekedwera kumatupi ndi ziwalo zina.
Zina mwazinthu zofunikira kwambiri m'thupi sizingayende bwino popanda L-carnitine. Kuperewera kwa chinthuchi kumatha kukhala chifukwa cha cholowa chobadwa nacho kapena matenda, mwachitsanzo, matenda a impso. Komanso, kuchepa kwa kaphatikizidwe ka L-carnitine kumatha kuyambitsa kumwa mankhwala ena, mwachitsanzo, meldonium.
Ndi kusowa kwa carnitine m'thupi, madokotala amapereka mankhwala omwe amabwezeretsa ndikusunga zomwe zili m'matumba. Pazithandizo, othandizira ma L-carnitine amagwiritsidwa ntchito pochiza matenda amtima ndi mitsempha, mitundu ina ya kupita patsogolo kwa minofu, thyrotoxicosis, kuchepa kwa ana, khungu ndi matenda ena ambiri.
L-carnitine amatengedwanso ndi anthu omwe amachita nawo masewera olimbitsa thupi. Masewera azakudya zopatsa thanzi okhala ndi amino acid amagwiritsidwa ntchito ngati mafuta othamangitsira njira zamagetsi.
Ndikulimbitsa thupi kwambiri, L-carnitine amathandizira kusintha mafuta acid kukhala mphamvu, motero tikulimbikitsidwa kuti tiwatenge kuti tithandizire kuchepetsa thupi komanso kuwotcha mafuta. Kutulutsidwa kwakukulu kwamphamvu kumathandizira kukulitsa luso la maphunziro powonjezera kupirira.
Poyamba anali kuganiza kuti L-carnitine imayambitsa ntchito za anabolic, koma lingaliro ili latsutsidwa. Komabe, zowonjezera ndi izi zimapitilizabe kutchuka pamasewera. Mukatengedwa pamodzi ndi steroids, zotsatira za L-carnitine zimakula.
Acetylcarnitine
Acetylcarnitine ndi mtundu wa ester wa L-carnitine womwe gulu la acetyl limalumikizidwa. Mosiyana ndi mitundu ina ya amino acid, imatha kuwoloka mu fyuluta yoteteza ubongo yotchedwa chotchinga magazi-muubongo.
Opanga zowonjezerazo nthawi zambiri amati acetylcarnitine ndi njira yatsopano komanso "yotsogola" ya L-carnitine, wothandizira masewerawa kwanthawi yayitali, motero amalimbikitsa anthu kugula zinthu zawo. Komabe, mukamagwiritsa ntchito mankhwala omwewo, mawonekedwe a acetyl m'magazi amakhala ochepa, ndiye kuti kupezeka kwake ndikotsika poyerekeza ndi mtundu wosavuta wa levocarnitine. Chifukwa chake, simuyenera kudalira malonjezo a otsatsa.
Ngati cholinga cha munthu ndikuchepetsa thupi, onetsetsani kuchuluka kwa mafuta m'thupi, ndiye kuti zowonjezera ndi L-carnitine momwe zimakhalira kapena mwa tartrate ndizabwino. Koma kuthekera kwa mawonekedwe a acetyl kuthana ndi cholepheretsa magazi ndiubongo chimagwiritsidwa ntchito kwambiri ngati mankhwala pothandizira komanso pochotsa.
Acetylcarnitine imalowa mkati mwa minyewa yapakatikati yamanjenje, potero imakulitsa kuchuluka kwathunthu kwa carnitine muubongo. Katundu wa acetylcarnitine amatheketsa kugwiritsa ntchito mankhwala osokoneza bongo potengera matenda ndi mikhalidwe:
- Matenda a Alzheimer;
- matenda amisala;
- zotumphukira za m'mitsempha, mosasamala komwe zimachokera;
- mtima encephalopathy ndi syndromes zosagwirizana zomwe zimachitika kumbuyo kwawo;
- kuwonongeka kwa magwiridwe antchito am'maganizo, kuphatikizapo kusintha kwaukalamba, komanso kuchepa kwa magwiridwe antchito a ubongo motsutsana ndi kuledzera kwakanthawi (mwachitsanzo, mowa);
- kutopa kwambiri kwanzeru;
- kuchepa kwamaganizidwe mwa ana.
Acetylcarnitine imagwiritsidwa ntchito ngati neuroprotector, mankhwala a neurotrophic, ali ndi cholinomimetic effect, popeza kapangidwe kake kofanana ndi neurotransmitter acetylcholine.
Ndibwino kuti musinthe kufalikira kwa ubongo, kumapangitsanso kusinthika kwa mitsempha.
Akafuna ntchito
Opanga osiyanasiyana amalimbikitsa mitundu yosiyanasiyana ya mayendedwe. Kawirikawiri, masewera olimbitsa thupi a acetylcarnitine amalangizidwa kuti amwe asanadye kapena nthawi ya chakudya, ndi maola 1-2 musanachite masewera olimbitsa thupi. Mankhwala ochokera pachipindachi amamwa mosasamala kanthu za chakudya.
Chofunikira cha tsiku ndi tsiku cha carnitine sichinakhazikitsidwe chifukwa sichinthu chopatsa thanzi.
Mulingo woyenera kwambiri umayesedwa kuti ndi 500-1,000 mg wa acetylcarnitine weniweni pa mlingo. Amapezeka mu makapisozi onse ndi ufa wokonzanso madzi.
Ndi kugwiritsa ntchito mankhwala ndi zowonjezera mavitamini ndi acetylcarnitine, zotsatira zoyipa sizimawoneka. Nthawi zina, nseru, kutentha pa chifuwa, kugaya chakudya, kupweteka kwa mutu ndizotheka, koma, mwalamulo, zotere zimakhudzana ndi kugwiritsa ntchito ndalama molakwika, kusintha kosintha kwa Mlingo.
Contraindications phwando ndi mimba, yoyamwitsa, tsankho munthu.
Onetsetsani kuti mwaonana ndi dokotala musanagwiritse ntchito mankhwala ndi acetylcarnitine kwa anthu omwe akudwala matenda otsatirawa:
- aimpso, kulephera kwa chiwindi;
- khunyu;
- matenda a mtima, mitsempha;
- kuphwanya kwa kuthamanga kwa magazi (zonse kumawonjezera ndi kuchepa);
- matenda enaake;
- matenda ashuga;
- mavuto ogona;
- kupuma kwa ntchito.
Acetylcarnitine ndi hydrolyzed m'magazi, omwe atha kuwonetsa kuchepa kwachilengedwe. Ubwino wa mankhwalawa pamasewera kuposa mitundu yonse ya L-carnitine ndizokayikitsa, ndipo mtengo wama zowonjezera nawo ndiwokwera kwambiri.
Mwina sizomveka kugula zakudya zowonjezera mtengo ndi acetylcarnitine. Kumbali inayi, chinthuchi chimathandizanso pakupanga mphamvu panthawi yochita masewera olimbitsa thupi, komanso kukhala ndi phindu pantchito zamaubongo.
