Amino acid ndi mankhwala omwe amapanga mapuloteni. Pakati pawo pali zina zomwe thupi lathu limatha kuzisintha, ndi zina zosasinthika zomwe zimabwera ndi chakudya chokha. Zofunikira (zofunika) zimaphatikizapo ma amino acid asanu ndi atatu, kuphatikiza isoleucine - L-isoleucine.
Ganizirani za isoleucine, mankhwala ake, zomwe zingagwiritsidwe ntchito.
Katundu wa mankhwala
Kapangidwe ka isoleucine ndi HO2CCH (NH2) CH (CH3) CH2CH3. Katunduyu ali ndi zida zochepa za acidic.
Amino acid isoleucine ndi gawo limodzi mwa mapuloteni ambiri. Imagwira ntchito yofunikira pakumanga maselo amthupi. Popeza chipangizocho sichinapangidwe chokha, chimayenera kuperekedwa ndi chakudya chokwanira. Isoleucine ndi unyolo wa amino acid.
Ndikusowa kwa zinthu zina ziwiri zomanga thupi zamapuloteni - valine ndi leucine, kompositi imatha kusandulika pakakhala kusintha kwamankhwala ena.
Udindo wamthupi umaseweredwa ndi L-mawonekedwe a isoleucine.
Mankhwala
Amino acid ndi wa othandizira anabolic.
Pharmacodynamics ndi pharmacokinetics
Isoleucine imakhudzidwa pakupanga mapuloteni a fiber. Mukamamwa mankhwala okhala ndi amino acid, chogwiritsira ntchito chimadutsa chiwindi ndikupita minofu, yomwe imathandizira kuchira pambuyo pa microtraumatization. Malo ogwiritsira ntchito amagwiritsidwa ntchito kwambiri pamasewera.
Monga gawo la michere, thunthu kumawonjezera erythropoiesis m`mafupa - mapangidwe maselo ofiira, ndipo mwina nawo trophic ntchito zimakhala. Amino acid imagwira ntchito ngati gawo logwirira ntchito mwamphamvu kwamankhwala, imathandizira kugwiritsa ntchito shuga.
Thunthu ndi mbali yofunika ya microflora matumbo, ali ndi zotsatira bactericidal motsutsana ena tizilombo toyambitsa matenda.
Kusintha kwakukulu kwa isoleucine kumachitika mu minofu ya mnofu, pomwe imapangidwa decarboxylated ndikupitilira mkodzo.
Zisonyezero
Mankhwala ozunguza bongo a Isoleucine amalembedwa:
- monga gawo la zakudya za makolo;
- asthenia motsutsana ndi matenda aakulu kapena njala;
- kupewa matenda a Parkinson ndi matenda ena amitsempha;
- ndi matenda am'mimba amitundu yosiyanasiyana;
- mu nthawi yokonzanso pambuyo povulala kapena kuchitidwa opaleshoni;
- mu pachimake ndi matenda yotupa matumbo;
- monga gawo limodzi la mankhwala ovuta komanso kupewa matenda am'magazi ndi mtima.
Zotsutsana
Contraindications kumwa isoleucine:
- Kusokoneza magwiritsidwe amino acid. Matendawa amatha kuyambitsidwa ndi matenda amtundu wina omwe amabwera chifukwa chosowa kapena kusakwanira kwa michere yomwe imakhudzidwa ndikuwonongeka kwa isoleucine. Pachifukwa ichi, kudzikundikira kwa ma organic acid kumachitika, ndipo acidemia imayamba.
- Acidosis, yomwe idawonekera motsutsana ndi matenda osiyanasiyana.
- Matenda a impso ndi kuchepa kwamphamvu pakusefera kwamagetsi.
Zotsatira zoyipa
Zotsatira zoyipa mukamamwa isoleucine ndizosowa. Milandu ya thupi lawo siligwirizana, amino acid tsankho, nseru, kusanza, kusokonezeka tulo, kupweteka kwa mutu, kuwonjezeka kwa kutentha kwa thupi mpaka kuzinthu zochepa zomwe zafotokozedwa. Maonekedwe osafunikira nthawi zambiri amathandizidwa ndi kuchuluka kwa mankhwalawa.
Malangizo ntchito
L-isoleucine amapezeka m'mankhwala ambiri. Njira ya makonzedwe, kutalika kwa maphunziro ndi mlingowo zimadalira mtundu wa mankhwala ndi malingaliro a dokotala wopezekapo.
Zowonjezera masewera ndi isoleucine zimatengedwa pamlingo wa 50-70 mg pa 1 kg ya kulemera kwa thupi.
Musanagwiritse ntchito zowonjezera zakudya, muyenera kuwerenga malangizowo, chifukwa mlingowu umasiyana. Kutalika kwa kutenga chowonjezeracho kumadalira mawonekedwe amunthuyo.
Bongo
Kupitilira muyeso wololedwa wambiri kumabweretsa chizungulire, kunyansidwa, ndi kusanza. Organic acidemia imayamba. Izi zimatulutsa fungo la thukuta ndi mkodzo, kukumbukira matapo a mapulo. Pakakhala zovuta kwambiri, mawonekedwe amanjenje, kupweteka, kupuma, komanso kuwonjezeka kwa impso ndizotheka.
Matupi awo sagwirizana ngati chikanga, dermatitis, conjunctivitis ndi kotheka.
Mankhwala osokoneza bongo cholinga chake ndi kuthetsa zizindikiro ndikuchotsa isoleucine wambiri m'thupi.
Kuyanjana
Palibe kuyanjana kwa isoleucine ndi mankhwala ena omwe adadziwika. Mgwirizanowu umadutsa chotchinga magazi ndiubongo ndipo umatha kuletsa pang'ono tryptophan ndi tyrosine.
Kutengera kwakukulu kumadziwika ndikudya munthawi yomweyo kophatikizana ndi mafuta azamasamba ndi nyama.
Zogulitsa
Mankhwala a amino acid amapezeka popanda mankhwala.
Malangizo apadera
Pamaso pa matenda opunduka amtima, makina opumira komanso matenda a impso, ndizotheka kuchepetsa kuchepa kwa mankhwalawa.
Sikoyenera kuphatikiza phwando ndi folic acid, chifukwa kompositi imachepetsa kusakanikirana kwake.
Mgwirizanowu umaperekedwa mosamala kwa odwala omwe ali ndi mtima wam'mimba, chifukwa amino acid amachepetsa kuchuluka kwa sodium ndi potaziyamu m'magazi.
Pa mimba ndi mkaka wa m'mawere
Mankhwala ali mgulu la FDA la A, ndiye kuti, samapereka chiopsezo kwa mwana.
Isoleucine owonjezera komanso kuchepa
Kuchulukitsa kwa isoleucine kumabweretsa kukulira kwa acidosis (kusintha kosasintha kwa thupi mpaka acidity) chifukwa cha kuchuluka kwa zidulo zamagulu. Pa nthawi imodzimodziyo, zizindikiro za kufooka kwa thupi, kuwodzera, mseru zimawonekera, ndipo kusinthasintha kumachepa.
Kuchuluka kwa acidosis kumawonetseredwa ndi kusanza, kuthamanga kwa magazi, kufooka kwa minofu, kusowa chidwi, matenda a dyspeptic, kuchuluka kwa kugunda kwa mtima ndi mayendedwe opumira. Matenda omwe amabwera chifukwa cha kuchuluka kwa isoleucine ndi ma amino acid omwe ali ndi nthambi zambiri ali ndi nambala ya ICD-10 E71.1.
Kuperewera kwa Isoleucine kumawoneka ndi zakudya zosamalitsa, kusala kudya, matenda opatsirana am'mimba, hematopoietic system ndi matenda ena. Pa nthawi yomweyo, kuchepa kwa njala, mphwayi, chizungulire, kugona tulo.
Isoleucine mu chakudya
Kuchuluka kwambiri kwa amino acid kumapezeka mu zakudya zokhala ndi mapuloteni ambiri - nkhuku, ng'ombe, nkhumba, kalulu, nsomba zam'madzi, chiwindi. Isoleucine imapezeka muzakudya zonse za mkaka - mkaka, tchizi, kanyumba tchizi, kirimu wowawasa, kefir. Kuphatikiza apo, zakudya zamasamba zimakhalanso ndi chopindulitsa. Amino acid ndi wolemera kwambiri mu soya, watercress, buckwheat, mphodza, kabichi, hummus, mpunga, chimanga, amadyera, zinthu zophika, mtedza.
Gome likuwonetsa zofunikira tsiku ndi tsiku za amino acid kutengera moyo.
| Kuchuluka kwa amino acid mu magalamu | Moyo |
| 1,5-2 | Zosagwira |
| 3-4 | Wamkati |
| 4-6 | Yogwira |
Kukonzekera komwe kuli
Mgwirizanowu ndi gawo la:
- mankhwala othandizira makolo ndi zakudya zopatsa thanzi - Aminosteril, Aminoplasmal, Aminoven, Likvamin, Infezol, Nutriflex;
- vitamini maofesi - Moriamin forte;
- nootropics - Cerebrolysate.
M'masewera, amino acid amatengedwa ngati ma BCAA othandizira okhala ndi isoleucine, leucine ndi valine.
Ambiri ndi awa:
- Optimum Nutrition BCAA 1000;
- BCAA 3: 1: 2 kuchokera ku MusclePharm;
- Amino Mega Wamphamvu.
Mtengo
Mtengo wa mankhwala a Aminovena pa zakudya zopatsa thanzi ndi ma 3000-5000 ma phukusi, omwe amakhala ndi matumba 10 a 500 ml ya yankho.
Mtengo wa chidebe chimodzi chowonjezera pamasewera chomwe chili ndi amino acid wofunikira chimadalira voliyumu ndi wopanga - kuyambira ma ruble 300 mpaka 3000.
