Hormone yogona (melatonin) - chomwe chiri ndi momwe zimakhudzira thupi la munthu

Monga mukudziwa, palibe chomwe chimachitika m'thupi la munthu popanda chifukwa. Hormone yogona (dzina lasayansi - melatonin) ndiye chifukwa chake anthu amakopeka usiku. Lero tikukuwuzani momwe melatonin imakhudzira thupi la munthu komanso momwe mungathetsere kugona. Tiganiziranso mankhwala othandiza kwambiri pakubwezeretsa kugona ndikubwezeretsanso magwiridwe antchito.

Timayankhula za hormone yogona m'mawu osavuta

Zambiri pamoyo wathu zimadalira pakupanga kolondola kwa zinthu zina ndi thupi. Melatonin ndi imodzi mw mahomoni ofunikira kwambiri amunthu. Iye ali ndi udindo wopanga ma biorhythms. Zisokonezo pantchito ya chinthuchi zimayankha mavuto atulo, kukhumudwa, kusokonezeka kwa kagayidwe kachakudya ndikuchepetsa chiyembekezo cha moyo.

Melatonin ingafanane ndi woyang'anira magalimoto. Kapena ndi wochititsa. Mahomoni amawongolera "anzawo" ndipo amatumiza ma cell kuti ndi nthawi yokonzekera kusintha kwakanthawi m'moyo. Tithokoze iye, machitidwe amthupi amatsegulidwa munjira ina, kutilola kuti tigone ndikupeza bwino.

Kuchuluka kwa melatonin kumachepa pazaka zambiri. Kwa makanda, kutulutsa kwa hormone iyi kumakhala kowirikiza kakhumi kuposa kwa munthu wamkulu. Ichi ndichifukwa chake mzaka zoyambirira za moyo timagona tulo mosavuta, ndipo tulo timakhala titalitali komanso tabwino. Chifukwa cha kuchepa kwa mahomoni, nthawi zambiri zimakhala zovuta kuti okalamba azipereke kwa Morpheus ndi Hypnos.

Ntchito ndi magwiridwe antchito a melatonin

Kupanga kwa tulo timankhwala tomwe timapezeka mu pineal gland (pineal gland), yomwe ili pakatikati pa ubongo, kuchokera ku amino acid tryptophan.

Pineal gland ndiye chiwalo chachikulu chomwe chimatumizira zidziwitso zathupi lanu za kayendedwe kabwino ka malo ozungulira.

Serotonin, hormone ya chisangalalo, imapangidwanso pano. Zinthu zomwezo ndizomwe zimayambitsa melatonin ndi serotonin. Izi makamaka zimafotokozera zovuta zomwe zimakhudzana ndimavuto a melatonin synthesis (gwero - Wikipedia).

Matenda a pineal siwo okha omwe amapanga "tulo". Munjira yam'mimba, imapitilira maulendo ambirimbiri kuposa muubongo. Koma m'magawo am'mimba, melatonin imagwira ntchito mosiyana ndipo siyikhala ngati timadzi tating'onoting'ono. Impso ndi chiwindi zimatulutsanso, koma pazifukwa zosiyana, zosagwirizana ndi kugona.

Hormone yogona ndi "beacon" yomwe imadziwitsa thupi zakumadzulo. Ndipo kukhala olondola kwambiri - zakumdima.

Chifukwa chake, zikanakhala zolondola kwambiri kutcha chinthu ichi hormone yakusiku. Limagwirira kaphatikizidwe ake amagwirizana ndi wotchi yachilengedwe, yomwe imayang'anira gawo loyang'ana kutsogolo kwa hypothalamus. Kuchokera apa, chizindikiro chimapita kumtunda wa pineal kudzera mu diso ndi dera lachiberekero la msana.

Maselo onse m'thupi amakhala ndi nthawi yokhazikika. Ali ndi "oyimba" awo, koma ma cell amatha kusinthitsa nthawi. Mwa zina, melatonin amawathandiza pa izi. Ndi amene amauza maselo kuti kuli madzulo kunja kwawindo ndipo muyenera kukonzekera usiku.

Kuti mibadwo ya melatonin isalephere, thupi liyenera kugona. Ndipo kugona bwino, mdima ndikofunikira kwambiri. Kuwala - kwachilengedwe kapena kopangira - kumachepetsa kwambiri mphamvu ya kaphatikizidwe ka mahomoni. Ndiye chifukwa chake, poyatsa nyali, timasokoneza tulo.

Ngati gawo la chinthuchi mthupi ndilotsika, tulo chimataya ntchito yake yobwezeretsa - imakhala yachiphamaso. Popeza kulumikizidwa kwa serotonin, ndizomveka chifukwa chake kusowa tulo kumalumikizidwa nthawi zonse ndi kusakhala bwino.

Mndandanda wa ntchito za melatonin:

• kuwongolera magwiridwe antchito a endocrine system;
• amachepetsa calcium kuyenda mu mafupa;
• ndi chimodzi mwa zinthu zomwe zimayendetsa kuthamanga kwa magazi;
• kutalikitsa magazi nthawi;
• mathamangitsidwe wa mapangidwe chitetezo;
• kuchepa kwa nzeru, malingaliro ndi zochitika zolimbitsa thupi;
• kuchepetsa kutha msinkhu;
• malamulo a nyengo zoyipa;
• zotsatira zabwino pakusinthira pakusintha nthawi;
• kuchulukitsa zaka za moyo;
• kugwira ntchito ya antioxidants;
• kumawonjezera chitetezo chokwanira.

Momwe timadzi tomwe timapangidwira timapangidwira

Kuchuluka kwa zopangidwa ndi melatonin kumangirizidwa ndi nyimbo za circadian. Pafupifupi 70% ya mahomoni amatulutsidwa pakati pausiku mpaka 5 koloko m'mawa. Munthawi imeneyi, thupi limapanga 20-30 μg wazinthuzo. Kuzama kwakukulu kwa anthu ambiri kumachitika 2 koloko m'mawa. Kuwonjezeka kwa kaphatikizidwe kumayamba ndikayamba madzulo. Kuphatikiza apo, kuyatsa kulikonse kumatha kuyimitsa kaphatikizidwe. Chifukwa chake, ndibwino kusiya kugwira ntchito pakompyuta kapena kugwiritsa ntchito foni ya foni osachepera maola angapo musanagone.

Koma izi sizitanthauza kuti kupezeka kwathunthu kwa kuwala kumatha kubweretsa kuchuluka kwa mahomoni.

Kuunikira kukuwunika ndiye chisonyezo chachikulu chomwe chikusonyeza kuti gland ya pineal imagwedeza ntchito, koma osati yokhayo.

Mwachizolowezi, momwe magwiridwe antchito amakhalira ovuta kwambiri, chifukwa chake timazolowera zovuta ndi zosowa za thupi. Mphamvu zikangobwezeretsedwa, kufunika kwakumwa kwakukulu kwa melatonin kudzatha (gwero - monograph ya Pulofesa V. N. Anisimov "Melatonin: gawo m'thupi, kugwiritsa ntchito zamankhwala").

Zolemba za Melatonin

Mahomoni opangidwa atagona amapezeka kunja. Amapezeka mu chakudya ndi kukonzekera kwapadera.

Mu chakudya

Pali zakudya za melatonin mu zakudya, koma kuchuluka kwake ndi kocheperako kotero kuti sikungakhale ndi zotsatira zowoneka.

Kumbukirani kuti thupi limapanga palokha mpaka 30 μg wa melatonin patsiku. Ndiye kuti, zochulukitsa mazana kuposa zomwe munthu angalandire ngakhale mtedza.

Melatonin amachita ngati antioxidant mu zakudya. Imagwira chimodzimodzi mthupi - imateteza DNA ndikuletsa zovuta zoyipa za oxidative. Mwachidule, mahomoni omwe amapangidwa nthawi yogona ndi ofunikira kuti muchepetse ukalamba.

Pokonzekera

Popeza kaphatikizidwe ka melatonin kamachepa ndi ukalamba, anthu ambiri amayenera kulipirira vuto la mahomoni ndi mankhwala. Ku Russia, mankhwala okhala ndi melatonin amawerengedwa kuti ndi zakudya zowonjezera ndipo amagulitsidwa popanda mankhwala. Katunduyu amagulitsidwa pansi pazizindikiro "Tsirkadin", "Sonovan", "Melaxen", ndi zina zambiri.

Muyenera kulabadira mlingo. M`pofunika kuyamba ndi mlingo osachepera. Ndipo pokhapokha ngati zotsatira za mankhwala sizimveka kapena kufotokozedwa moperewera, mlingowo umakulitsidwa.

Mahomoni opangidwa ayenera kutengedwa kotala la ola asanagone, mumdima kapena mopepuka. Simuyenera kudya ola limodzi musanamwe mankhwalawa.

Ndikofunika kukumbukira kuti kumwa mapiritsi mowala kumataya tanthauzo - mphamvu ya zowonjezera zowonjezera imachepetsedwa kwambiri.

Nthawi zonse muzifunsa dokotala musanadye melatonin yokumba. M'mayiko ena, kugulitsa mankhwalawa ndikoletsedwa. Mulimonsemo, kudzipatsa nokha mankhwala kumatha kudzaza ndi mavuto azaumoyo.

Ndemanga ina. Ngati kusowa tulo kumayambitsidwa ndi zovuta, mapiritsi sangathandize. Monga kutsekemera kwachilengedwe komwe sikungathandize. Ndipo ichi ndi chifukwa china cholingalirapo musanapemphe thandizo la mankhwala.

Kuwonongeka kwa melatonin wambiri

Ngakhale adotolo sakuletsa kumwa mapiritsi a melatonin, simuyenera kukhala achangu. Kuchulukitsa kumapangitsa kuti thupi lizipanga timadzi tating'ono (gwero - PubMed).

Chifukwa cha kuphwanya kwachilengedwe kwachilengedwe, munthu amatha kuyembekezera:

• kuwonjezeka kwa matenda aakulu;
• mavuto ndi kukumbukira ndi kusinkhasinkha;
• kuthamanga;
• kutopa nthawi zonse ndi kuwodzera;
• kupweteka mutu.

Kuphatikiza apo, azimayi amatha kuthana ndi mavuto obereka.

Zotsutsana ndi kugwiritsa ntchito mankhwala ndi melatonin

Kukonzekera komwe kumakhala ndi melatonin ndikotsutsana:

• ana ndi achinyamata;
• ndi matenda a shuga;
• matenda a khunyu;
• anthu sachedwa kuthamanga magazi;
• Matenda a khansa;
• ndi njira zodziyimira pokha.

Amayi apakati ndi amayi omwe akufuna kutenga pakati nawonso samalangizidwa kumwa mapiritsi.

Mukamamwa mankhwala a melatonin ndi antidepressant nthawi yomweyo, muyenera kukhala okonzekera zovuta zomwe zingachitike.

Ndizofunikanso kwa anthu omwe ntchito yawo yantchito imalumikizidwa ndi kufunika kokhazikika kwa nthawi yayitali. Popeza melatonin imabweretsa ulesi, kunyalanyaza malangizowa kumadzaza ndi zosayembekezereka.

Onerani kanemayo: Melatonin Hormone. Sleep Hormone. Explained By Chandru in Tamil (January 2025).