Valine ndi amino acid wofunikira (katundu amene ali ndi zosowa za thupi)

Amino zidulo

3K 0 11/29/2018 (kukonzanso komaliza: 07/02/2019)

Valine ndi aliphatic (nthambi) amino acid amene ali mbali ya 70% ya mapuloteni, koma si apanga ndi thupi. Imagwira ngati matrix ophatikizira a pantothenic acid (vitamini B5) ndi penicillin (valinomycin). Mtengo wa amino acidwu ndi wovuta kuwunika kwambiri: thupi silimatha kugwira ntchito popanda ma L-L (L) ndi D (D) ma valine, popeza amapereka mphamvu yogwiritsidwa ntchito munyama zam'mimba ndipo amayendetsa kayendedwe ka thupi mlengalenga.

Khalidwe

Valine adapezeka koyamba m'malo a labotore mu 1901 ndi Emil Fischer wasayansi waku Germany ndi hydrolysis ya casein. Amino acid amatchulidwa ndi valerian chifukwa imagwira ntchito yolimbitsa thupi, potero imakhalabe yolimba.

Valine amafanana ndi leucine ndi isoleucine. Izi amino acid ndi hydrophobic, motero, pafupifupi inert mu njira zamagetsi ndi zamankhwala m'thupi, koma nthawi yomweyo imatsimikizira kukula kwa mapuloteni atatu ndipo imatha kuyamwa ma amino acid ena.

Valine amatchedwanso glucogenic amino acid kuti athe kugwiritsa ntchito isomers yake kukhala shuga m'chiwindi - gwero lofikirika kwambiri lamphamvu la minofu. Mofananamo, vitamini B3 imapangidwa kuchokera ku valine isomers.

Katundu mankhwala

Dzinalo la amino acid limafotokoza kuti malo ake akulu amakhudza dongosolo lamanjenje lomwe limayendetsa njira zolepheretsa ndi kusangalatsa.

Kuphatikiza apo, iye:

• imasonyeza zotsatira zolimbikitsa;
• kumapangitsa njira zosinthika m'thupi;
• kumawonjezera kupirira kwa minofu pazinthu zakunja;
• amakana kupsinjika ndi kupsinjika kwamaganizidwe;
• amateteza mwachangu kukula kwa uchidakwa ndi mankhwala osokoneza bongo;
• sikelo kagayidwe kake, kuchepetsa chidwi chofuna kudya ndikulimbikitsa kuchepa kwa thupi;
• amachepetsa malire a kumva kupweteka, makamaka akadziwitsidwa ndi kutentha;
• imayang'anira kupanga kukula kwa mahomoni, hemoglobin, kuchuluka kwa nayitrogeni mthupi;
• imathandizira matendawa ndi advanced sclerosis.

Zofunikira tsiku ndi tsiku

Munthu amafunika pafupifupi 2-4 g wa valine patsiku. Mlingo woyenera amawerengedwa pogwiritsa ntchito chilinganizo: 10 mg amino acid pa 1 kg yolemera thupi. Ngati pakufunika kuwonjezera mlingo, osati 10, koma 26 mg ya bio-zinthu amatengedwa ngati poyambira.

Kumbukirani kuti mukamamwa mankhwala a valine, kuwerengera kulikonse kwamankhwala kumapangidwa ndi dokotala, popeza pakompyuta ili ndi zotsutsana zazikulu zovomerezeka ndipo sizingangobweretsa phindu lokha, komanso kuvulaza. Pakakhala kulephera kwa chiwindi kapena impso, kuchepa kwa magazi m'thupi, matenda ashuga, matenda am'mimba, kugwiritsa ntchito amino acid kumakhala kochepa.

Zakudya

Popeza valine ndi amino acid wofunikira, kukhazikika kwake mthupi kumangodalira kudya kwake ndi chakudya. Amino acid wapamwamba kwambiri pazakudya zomwe zimagwirizana ndi zakudya zimaperekedwa patebulo.

B5 ndi B3 zimayamwa mosavuta kuchokera ku mtedza ndi mazira.

Zisonyezero

Valine tikulimbikitsidwa:

• ndi kukhumudwa, kusowa tulo;
• mutu waching'alang'ala;
• monga gawo lothandizira pakumwa uchidakwa ndi mankhwala osokoneza bongo;
• ndi kupsyinjika kwakuthupi;
• kusowa kwake mthupi;
• kunenepa kwambiri;
• kusokonezeka kwa magwiridwe antchito ndi chakudya;
• kuchotsa;
• kuvulala ndi kuphwanya umphumphu wa minofu.

Komabe, othamanga ambiri amafunikira amino acid wofunikira. Makamaka omwe akutenga nawo mbali pazolimba komanso maphunziro. Amazifuna kuti zithandizire kupangika kwa kagayidwe kachakudya, kupulumuka kwa minofu mukaphunzitsidwa, kuwonjezera minofu ya minofu, ndikuwonjezera kupirira konse. (nayi chisankho chabwino cha kupirira).

Zotsutsana

Valine nthawi zonse amalembedwa pambuyo pofufuza zachipatala ndi labotale ndipo amatsutsana ngati:

• matenda aakulu a chiwindi, impso, mtima;
• mimba ndi yoyamwitsa;
• ngati wodwalayo ali pansi pa 18;
• shuga, chiwindi, kagayidwe kachakudya matenda;
• tsankho payekha.

Zotsatira zoyipa

Mu nkhani ya bongo, zizindikiro za kuledzera anati: nseru, malungo, kusanza, palpitations mtima, delirium.

Kuperewera kwa valine kumawonetsedwa ndi kufooka komanso kutopa, kuwonongeka kwa ndende.

Kuyanjana ndi zinthu zina

Mukamamwa mankhwala osakaniza ndi mankhwala ena, m'pofunika kuganizira zochitika zake:

• amino acid nthawi zonse amatengedwa limodzi ndi leucine ndi isoleucine (kuchuluka kwake kumawerengedwa ndi dokotala);
• Valine sagwiritsidwa ntchito nthawi yofanana ndi tryptophan ndi tyrosine chifukwa imachepetsa kulowa kwawo m'maselo aubongo;
• amino acid mwangwiro odzipereka pa chakudya - ndi chimanga, muesli;
• kusowa kwa zinthu kumalepheretsa kuyamwa kwa ma amino acid ena.

Za owonjezera ndi kusowa kwa valine

Kusowa komanso kuchuluka kwa ma amino acid m'thupi kumabweretsa zizindikilo zoyipa. Chifukwa chake, muyenera kuwerenga mosamala malangizo amomwe mungagwiritsire ntchito mankhwalawa, makamaka pankhani ya mlingo.

Mopitirira malire:

• mavuto amanjenje: masomphenya, kunjenjemera, kutaya chidwi;
• mavuto ndi thermoregulation;
• Matenda am'mimba, kufooka kwa chiwindi ndi impso;
• kuchepetsa magazi, ma microcirculation.

Zoyipa zake zimayambitsa:

• njira zowononga m'matumbo;
• kuchepa kwa chitetezo;
• kuwonongeka kwa kukumbukira;
• kusowa tulo;
• kukhumudwa;
• zotupa pakhungu.

Amino acid amagulitsidwa m'masitolo ogulitsa ndi malo ogulitsira apadera. Mtengo umadalira wopanga, m'mphepete mwake ndi pafupifupi ma ruble 150-250 pa 100 g.

Onerani kanemayo: branced chain amino acid metabolism (January 2025).