Coenzyme Q10 ndi chinthu chomwe chimapangidwa ndi maselo amunthu ndipo chimagwira ntchito zake zofunika. Kuperewera kwake kumadzala ndi kukula kwa zovuta zazikulu. Pachifukwa ichi, kukwanira kwa thupi ndi michere yochokera kunja, kuchokera kuzowonjezera zamoyo komanso zakudya, kumakhala kothandiza.
Therapy ndi njira izi kumawonjezera kupirira, kubweza njira kuvunda ndi ukalamba, kumathandiza polimbana ndi Edzi, zotupa khansa, mtima ndi matenda ena ambiri.
Kodi ubiquinone ndi chiyani ndipo ndiwotani?
Ubiquinone ndi mtundu wa oxidized wa coenzyme wopezeka mu mitochondria, omwe ndi malo opumira ndi mphamvu ya selo iliyonse mthupi. Imalimbikitsa kupanga mphamvu mwa iwo mu mawonekedwe a ATP, amatenga nawo gawo pazonyamula zamagetsi pama cell.
Mwambiri, ubiquinone amachita izi:
- antioxidant - imalepheretsa kusintha kwaulere ndi mafuta owopsa, amachepetsa ukalamba;
- antihypoxic - zotsatira zake ndikuthandizira kusintha kwa mpweya m'thupi;
- angioprotective - kulimbitsa ndi kubwezeretsa kwa makoma a mitsempha, kuteteza magazi;
- kukonzanso - kubwezeretsa kwa nembanemba yama cell ndi kuthamanga kwa machiritso ovulala;
- immunomodulatory - lamulo la kagwiritsidwe ka chitetezo cha mthupi.
Mbiri yogwiritsa ntchito michereyi imayamba mu 1955-1957, pomwe idaphunziridwa koyamba ndikutsimikiza kwa kapangidwe kake ka mankhwala.
Dzinali linapatsidwa ku ubiquinone chifukwa cha kupezeka kwake, ndiye kuti paliponse.
Pa nthawi imodzimodziyo, chitukuko cha mankhwala ozikidwa pa izo chinayamba, chomwe chinagwiritsidwa ntchito pochita mu 1965 pochiza matenda amtima.
Ubiquinone imagwira ntchito bwino ndi zinthu zina zomwe zimakhudza mitochondria. Iye ali ndi udindo wopanga mphamvu, pokonza zomwe carnitine ndi thioctic acid zimakhudzidwa, ndipo creatine amalimbikitsa kutulutsidwa kwake (gwero - NCBI - National Center for Biotechnology Information).
Pachifukwa ichi, enzyme imagwiritsidwa ntchito pazinthu izi:
- kukhazikika kwa dongosolo la mtima ndi kuteteza kuthamanga kwa magazi;
- kukonza zotanuka zamakoma a mitsempha ndikuwalimbitsa;
- kuchepetsa kukula kwa cholesterol zolembera ndi zizindikiro za atherosclerosis;
- kupewa ndikuchepetsa matenda a Parkinson kapena Alzheimer's;
- kukonzekera kulimbitsa thupi kapena katundu wotalika;
- Chithandizo cha matendawa;
- kupewa matenda a khansa;
- chithandizo cha boma ngati atadwala;
- Kuchepetsa nthawi yokonzanso pambuyo pa matenda akulu komanso njira zopangira opaleshoni.
Njira yogwirira ntchito
Udindo wa Coenzyme Q10 ndikuyambitsa zochitika zingapo zomwe zimathandizira kuti chakudya chikhale mphamvu.
Kufotokozera kwa momwe zimayambira kumayambira ndi kaphatikizidwe ka ubiquinone, komwe kamapangidwa m'maselo ochokera ku mevalonic acid, zamagetsi zamagetsi a phenylalanine ndi tyrosine.
Imagwira nawo ntchito zoyendera ndi mphamvu, kutenga ma proton ndi ma elektroni kuchokera kumakonzedwe apakompyuta a I ndi II. Chifukwa chake amachepetsedwa kukhala ubiquinol, chinthu chogwira ntchito kwambiri chomwe chimachulukitsa kupezeka kwa bioavailability komanso kuthekera kolowera.
Chotsatiracho chimasamutsa ma electron awiri kupita kumalo opumira a III, omwe amatenga nawo gawo pakupanga adenosine triphosphoric acid (ATP) m'matumbo a mitochondrial. Zimakhudza mwachindunji kusintha kwaulere, kugwiritsa ntchito mphamvu ya antioxidant kumaselo owononga zinthu.
Zovuta pakukhala ndi moyo
Kutha kupanga ubiquinone ndipamwamba kwambiri ali mwana komanso pamaso pathupi mavitamini A, C, gulu B ndi onunkhira amino acid tyrosine.
Kwa zaka zambiri, kuchuluka kwake kumatsika mwachangu, ndipo chiwopsezo cha matenda chimakulirakulira, pomwe izi ndizofala:
- fibromyalgia - matenda a minofu ndi mafupa;
- matenda amtima ndi zovuta zawo;
- Prader-Willi matenda amtundu wa ana obadwa kumene;
- parkinsonism, limodzi ndi ulesi, kusakhazikika kwa mayendedwe ndi kunjenjemera kwa manja;
- Matenda a Huntington;
- amyotrophic lateral sclerosis;
- kunenepa kwambiri;
- matenda ashuga;
- kusabereka mwa amuna;
- kukanika kwa chitetezo cha mthupi, chomwe chingasinthe kukhala chimfine pafupipafupi, kudwala kwama autoimmune, zotupa zoyipa;
- kukhumudwa, migraines pafupipafupi, ndi zina zambiri.
Coenzyme Q yowonjezerapo atha kulembedwa kuti athetse matendawa kapena kuthana ndi mavuto omwe alipo kale.
Ngakhale kuti sichitalikitsa moyo, michere imakhala ndi mphamvu zotsutsana ndi ukalamba posungira thanzi la munthu.
Zotsatira pa thupi
Pokhala coenzyme wosungunuka mafuta, coenzyme imangotengeka mosavuta ndimatumba ndi ziwalo ikawalowa kuchokera kunja. Potengera ntchito, imafanana ndi mankhwala a vitamini, omwe amatsogolera ku dzina la pseudovitamin kapena vitamini Q10.
Kuchuluka kwake kumapezeka m'matumba omwe amakhala ndi mphamvu zamagetsi zambiri, monga mtima, impso ndi chiwindi.
Kuwonjezeka kwa michere kumayambitsa njira izi:
- kumawonjezera kupirira kwa othamanga;
- bwino zolimbitsa thupi mu ukalamba;
- amachepetsa kutayika kwa dopamine, mwina amateteza magwiridwe antchito mu matenda a Parkinson;
- kumalimbitsa zimakhala ndi kupewa kuwononga mphamvu ya cheza pa khungu, bwino ake elasticity ndi kusinthika;
- amachepetsa kuwonongeka kwa minofu ya mtima ndikuwonjezera moyo wa ziwalo zina;
- Kuchepetsa mitsempha, kumachepetsa kuthamanga kwa magazi ndikuwonjezera kuthamanga kwa magazi ngati walephereka;
- kumawonjezera kuchuluka kwa insulin ndi proinsulin, kumachepetsa kuchuluka kwa glycohemoglobin m'magazi, kumachepetsa chiopsezo cha matenda ashuga;
- kumawonjezera ntchito ya mapuloteni m'matumba a minofu, kuchepetsa kutopa ndikuchulukitsa kupirira pakumangika kwawo kwakukulu (gwero - NCBI - National Center for Biotechnology Information).
Coenzyme pamasewera
Coenzyme Q10, yomwe imapezeka ngati chowonjezera, imagwiritsidwa ntchito ndi othamanga kuti apititse patsogolo maphunziro awo, komanso kuti athetse zovuta zolimbitsa thupi. Kuphatikiza apo, Q10 ndiwowonjezera mphamvu kwa othamanga.
Zakudya zowonjezerazo zimachepetsa kuwonongeka kwa minofu chifukwa cha kuchepa kwa mpweya mwa iwo.
Katunduyu ndiwofunikira makamaka pochita maphunziro a anaerobic, kukwera pamwamba kwambiri.
Mlingo wa tsiku ndi tsiku wa mankhwala ndi 90-120 mg. Pogwiritsa ntchito zolimbitsa thupi, ndibwino kugwiritsa ntchito pafupifupi 100 mg kuphatikiza mavitamini C ndi E. Izi zithandizanso kuwonjezera mphamvu.
Zikuonetsa ntchito
Zizindikiro zogwiritsa ntchito ubiquinone zitha kukhala:
- kupsinjika kwakuthupi kapena kwamaganizidwe;
- zovuta, kupanikizika kwamaganizidwe;
- kuthamanga kapena kuthamanga kwa magazi;
- chemotherapy ndi opaleshoni;
- matenda opatsirana omwe amachepetsa chitetezo chamthupi;
- kusowa kwa chitetezo m'thupi mwa HIV ndi Edzi;
- chiopsezo cha matenda opatsirana pambuyo pake ndi kuwonjezereka pambuyo pa kupwetekedwa;
- kuchuluka kwa magazi m'magazi;
- kupewa kusabereka mwa amuna;
- kupuma matenda;
- magazi m'kamwa, matenda a periodontal,
- matenda ashuga;
- arrhythmia, angina pectoris ndi mavuto ena m'munda wamtima.
Kutalika kwa chikuonetseratu ndi mlingo anapereka payekha mothandizidwa ndi akatswiri.
Zotsutsana
Zotsutsana pakugwiritsa ntchito coenzyme ndi izi:
- Vuto la zilonda zam'mimba;
- kukulitsa glomerulonephritis;
- kuchepa kwa kugunda kwa mtima (zosakwana 50 kumenya pamphindi);
- kumvetsetsa kwa zigawo zina;
- mimba, mkaka wa m'mawere ndi zaka 18.
Malo owopsa amaphatikizaponso odwala omwe ali ndi matenda a khansa komanso amtima. Ngati alipo, supplementation iyenera kukambidwa ndi dokotala wanu.
Mafomu omasulidwa ndi momwe angagwiritsire ntchito
Ubiquinone amapangidwa mwa mawonekedwe azakudya zopatsa thanzi ndi kutulutsa kosiyanasiyana ndi ma analog ambiri ochokera kwa opanga osiyanasiyana:
- gelatin makapisozi ndi madzi pakati, bwino odzipereka kwa thupi (Doppelgertsaktiv, Forte, Omeganol, Kaneka);
- mapiritsi okhala ndi potaziyamu, magnesium ndi zinthu zina (Coenzyme Q10, Capilar cardio);
- Mavitamini Opangidwa Ndi Vitamini-Chewable Lozenges (ochokera ku Kirkman)
- madontho owonjezera zakumwa zabwino kudya ndi mafuta (Kudesan);
- Yankho la jekeseni wamitsempha (Coenzyme Compositum).
Mwambiri, thupi limafuna 50 mpaka 200 mg wa coenzyme patsiku ngati palibe matenda oopsa. Njira yogwiritsira ntchito - kamodzi patsiku, ndi chakudya, chifukwa amatanthauza zinthu zosungunuka ndi mafuta.
Pazifukwa zochiritsira, mlingowo ukuwonjezeka kokha ndi akatswiri pamaziko a kafukufuku komanso mbiri yonse ya kudwala. Mwachitsanzo, ndi matenda a Parkinson, zofunikira tsiku ndi tsiku zidzawonjezeka kangapo.
Ubwino ndi kuipa
Zina mwazabwino za Q10:
- kusintha kwamphamvu kwa odwala omwe ali ndi matenda amtima;
- kuthekera kogwiritsa ntchito kupewa komanso popanda mankhwala;
- zovuta pazamagulu onse;
- mathamangitsidwe a kukonzanso postoperative;
- kuchepetsa kukula kwa khansa;
- kuchuluka kupirira ndi kuchepa kutopa;
- Chitetezo cha kagwiritsidwe ntchito ngati malangizo atsatiridwa.
Zotsatira zoyipa zimawonekera pokhapokha ngati malangizowo sanatsatidwe.
Mankhwalawa alibe poizoni mthupi, pokhala chowonjezera chachilengedwe.
Koma bwino odzipereka ndi kudya tsiku zosaposa 500 mg mu zovuta mankhwala a matenda. Kupitilira muyeso kumabweretsa kudzimbidwa, koma alibe zovuta zina, ngakhale mutagwiritsa ntchito nthawi yayitali. Nthawi zina, kuchuluka kwambiri kumatha kupititsa patsogolo ukalamba, kusokonezeka tulo kapena zotupa pakhungu.
Kupewa
Malinga ndi malangizowo, coenzyme imatengedwa kuti iteteze ndikuchepetsa matenda ambiri, monga khansa, vuto la mtima, sitiroko. Kuphatikiza apo, ndiyothandiza kuthana ndi vutoli ndikusunga kamvekedwe ka thupi.
Kufunika kwa zakudya zowonjezera zakudya kumachitika chifukwa cha kuchepa kwa kapangidwe ka ma enzyme ndi zaka pambuyo pa zaka 20.
Moyang'aniridwa ndi dokotala woyenera, zowonjezera zowonjezera zitha kugwiritsidwa ntchito mosalekeza, ngati palibe zovuta zina kapena zotsutsana.
Kafukufuku Waposachedwa
Malinga ndi kuyesa kwasayansi, komwe kumachitika koyamba pa mbewa, ubale udapezeka pakati pa mulingo wa coenzymes ndi kuchuluka ndi kapangidwe ka chakudya. Ngati kuchuluka kwa kalori kuli kochepa, ndiye kuti kuchuluka kwa Q9 ndi Q10 kumawonjezeka m'mafupa ndi impso, ndipo Q9 yokha imachepa m'matenda amtima.
M'mikhalidwe yamakono ku Italy, kuyesa kunachitika pakati pa odwala omwe ali ndi matenda amtima. Mwa maphunziro 2,500, ena mwa odwalawo adatenga zowonjezerazo kuphatikiza ndi mankhwala ena akuchipatala. Zotsatira zake, kusintha kudawona osati thanzi labwino, komanso khungu ndi tsitsi, komanso mavuto atulo adasowa. Anthu adazindikira kuwonjezeka kwa kamvekedwe ndi magwiridwe antchito, kutha kwa mpweya wochepa komanso mawonekedwe ena osasangalatsa.
