Dzina lachilatini la mankhwalawa ndi Regaine. Minoxidil
Regaine ndi chiyani?
Regaine ndi chithandizo chamankhwala cha alopecia (dazi) mwa amuna ndi akazi.
Kufotokozera kwa mawonekedwe a mlingo
Regaine amabwera ngati yankho lam'mutu. Itha kukhala 2% ndi 5%. Njirayi ndi yowonekera ndipo ili ndi mtundu wachikaso wonyezimira kapena wopanda mtundu. Imaphatikizidwa m'mabotolo a 60 ml. Phukusili mulinso miphuno itatu: nozzle wa kutsitsi, nozzle wopaka, ndi nozzle wowonjezera wopopera. The zikuchokera mankhwala, kupatula minoxidil 5 kutengera mafuta a ethanol, propylene glycol ndi madzi oyera.
mankhwala
Regaine ndi mankhwala omwe amathandizira pakukula kwa tsitsi mwa anthu omwe ali ndi vuto la androgenic alopecia. Pambuyo pa miyezi 4 yogwiritsa ntchito mankhwalawa, zizindikilo zakukula kwa tsitsi zimadziwika. Tiyenera kudziwa kuti kuyambika ndi kuuma kwa zotsatirazi kumasiyana malinga ndi wodwala. Zotsatira zachangu zimapezedwa ndi yankho la 5% regain, poyerekeza ndi yankho la 2%. Izi zadziwika chifukwa cha kuchuluka kwa kukula kwa tsitsi la vellus. Koma kutha kwa kugwiritsa ntchito mankhwalawa, kukula kwa tsitsi latsopano kuyimitsidwa, ndipo m'miyezi 3-4 ikubwerayi mwayi wakubwezeretsanso mawonekedwe apachiyambi ukuwonjezeka. Machitidwe a Regaine pochiza androgenic alopecia samamveka bwino.
Pharmacokinetics
Minoxidil imayamwa bwino kudzera pakhungu labwinobwino komanso losasunthika ikamagwiritsidwa ntchito kunja. Chizindikiro ichi chimakhala ndi 1.5%, ndipo mtengo wake wokwera ukhoza kufikira 4.5%. Awo. 1.5% yokha ya mankhwala omwe angagwiritsidwe ntchito ndi omwe amatha kulowa m'magulu azinthu zonse. Zotsatira za matenda opatsirana pakhungu pakamwa kwa mankhwala sizikudziwika.
Mpaka pano, mbiri ya kagayidwe kachakudya ka minoxidil kachirenso katatha ntchito yakunja sikanaphunzirebe kwathunthu.
Minoxidil samalowa mu BBB ndipo samangiriza mapuloteni am'magazi am'magazi.
Pafupifupi 95% ya minoxidil yomwe imalowa mu kayendedwe kake kamatulutsidwa mkati mwa masiku 4 otsatira pambuyo posiya kumwa mankhwala.
Regaine amatulutsidwa kwambiri mumkodzo. Izi zimachitika ndi kusefera kwama glomerular.
Mothandizidwa ndi hemodialysis, minoxidil ndi metabolites amachotsedwa mthupi.
Zikuonetsa mankhwala
Chizindikiro cha kugwiritsidwanso ntchito ndi androgenic alopecia, onse amuna ndi akazi. Amaperekedwa kuti akhazikitse tsitsi, komanso kubwezeretsa khungu.
Zotsutsana
Regaine sayenera kugwiritsidwa ntchito ndi ana komanso achinyamata azaka zosakwana 18, komanso odwala azaka zopitilira 65. Kuphwanya umphumphu ndi khungu la m'mutu, hypersensitivity kuzipangizo za mankhwala ndizotsutsana.
Ntchito pa mimba ndi mkaka wa m'mawere
Ngakhale kuti mphamvu yobwezeretsanso wodwalayo panthawi yoyembekezera ndi kuyamwitsa sikudziwika, sayenera kugwiritsidwa ntchito. Pogwiritsidwa ntchito pafupipafupi, minoxidil imasakanikirana ndikutulutsa mkaka wa m'mawere.
Zotsatira zoyipa za mankhwala
Kafukufuku wamankhwala awonetsa kuti dermatitis, yomwe imachitika pakhungu, imatha kukhala yoyipa. Nthawi zambiri, kutupa, khungu, kufiira kumawonetsedwa.
Matupi kukhudzana dermatitis ndi kuyabwa khungu, alopecia ndi folliculitis ndi osowa.
Tiyenera kukumbukira kuti zotsatira zoyipa zimawonekera nthawi zambiri mukamagwiritsanso ntchito ngati 5% yankho.
Komanso, mukamagwiritsa ntchito mankhwalawa, matupi awo sagwirizana ndi mpweya komanso kupuma movutikira, chizungulire komanso kupweteka mutu, matenda am'mimba, kusinthasintha kwa kuthamanga kwa magazi komanso kupweteka kwamtima, kupweteka pachifuwa, kusintha kwa magwiridwe antchito amtima. Koma kulumikizana momveka bwino pakati pa kugwiritsa ntchito mankhwalawa ndi kupezeka kwa zovuta kumadziwika, makamaka, ndi zomwe zimachitika pakhungu.
Bongo
Kuchulukitsitsa kumatha kuchitika ngati mwangozi mutatenga Regaine mkati. Izi zimayambitsa machitidwe amachitidwe, omwe amachokera ku vasodilating katundu wa chigawo chachikulu cha mankhwala, minoxidil.
Zizindikiro za zodabwitsazi ndi monga tachycardia, kuchepa kwa kuthamanga kwa magazi ndi kusungira kwamadzimadzi.
Pakakhala mankhwala osokoneza bongo, m'pofunika kupeza chithandizo chamankhwala kuti mupereke mankhwala omwe angapangitse kukana.
Njira ya makonzedwe ndi mlingo
Regaine imangopangidwira ntchito yakunja pamutu. Sikulimbikitsidwa kuti mugwiritse ntchito ziwalo zina za thupi.
Mlingo wathunthu wamankhwala tsiku lililonse sayenera kupitirira 2 ml, mosasamala kanthu za dera lomwe lakhudzidwa. Ndibwino kugawa ndalamayi muyezo 2 wa 1 ml. Kubwezeretsanso kuyenera kugwiritsidwa ntchito kuchokera pakatikati pa zilondazo mpaka m'mphepete.
Tikulimbikitsidwa kugwiritsa ntchito yankho la 5% pokhapokha ngati wodwala yemwe amagwiritsa ntchito yankho la 2% alibe zokongoletsa zokhutiritsa pakukula kwa tsitsi, ndipo zotsatira mwachangu ndizofunikira.
Amayi amalangizidwa kuti azigwiritsa ntchito mankhwalawa pakutha kwa tsitsi m'dera losiyana. Amuna, komano, amagwiritsa regaine kutaya tsitsi kumachitika pa korona. M'maderawa, mankhwalawa ndi othandiza kwambiri.
Gulaninso, ndiyeno iyenera kupakidwa pakhungu louma. Njira yogwiritsira ntchito imadalira omwe akugwiritsa ntchito. Ngati mankhwalawa agwiritsidwa ntchito ndi nsonga, ndiye kuti ayenera kutsukidwa bwino atachiza mutu.
Ngati regaine wapakidwa ndi botolo la kutsitsi, chotsani kapu yayikulu yayikulu m'botolo komanso kapu yamkati. Kenako ndikofunikira kukhazikitsa botolo lofunikira (kutsitsi) pa botolo ndikulipukuta mwamphamvu. Mutu wa kamwa kali pakati pa dera lomwe muyenera kulandira mankhwala, perekani wothandizirayo ndikugawana chimodzimodzi ndi zala zanu. Zokwanira kubwereza njira izi kasanu ndi kamodzi (1 ml).
Ngati dera lomwe lakhudzidwa ndi laling'ono kapena pansi pa tsitsi lotsalira, ndibwino kuti mugwiritse ntchito mphuno yowonjezera. Njira zoyambirira zogwiritsa ntchito cholumikizirachi ndizofanana ndi m'mbuyomu. Kenako chotsani mutu wawung'ono kutsitsi mfuti ya kutsitsi ndikulimbikitsanso mphutsi yogawa. Kukonzekera kumeneku kuyeneranso kufalikira ponseponse ndi zala zanu ndipo njirayi iyenera kubwerezedwa kasanu ndi kamodzi.
Pofunsira kumadera ang'onoang'ono a dazi, gwiritsani ntchito mphuno yopaka. Ikani pa botolo, mukulumikiza mwamphamvu, ndikufinya botolo kuti mudzaze chipinda chapamwamba ndi mzere wakuda (1 ml). Kenako, ndikutikita minofu, mankhwalawa amagwiritsidwa ntchito kudera lomwe lakhudzidwa.
malangizo apadera
Musanagwiritse ntchito Regaine, muyenera kukayezetsa kwathunthu kuti muwonetsetse kuti khungu lakelo ndilabwino.
Kugwiritsiridwa ntchito kwa mankhwala kuyenera kuthetsedwa ngati zingachitike pakhungu lalikulu komanso zotsatirapo zoyipa.
Migwirizano ndi zokwaniritsa zosunga
Alumali moyo wa regain umatengera yankho: yankho la 5% limasungidwa zaka 5, 2% kwa zaka zitatu. Sungani mankhwalawa pamalo ouma osafikira ana, pomwe kutentha sikupitilira 25 ° C.
